DEPARTMENT OF VET. PHARMACOLOGY & TOXICOLOGY

WELCOME TO THE DEPARTMENT OF VET. PHARMACOLOGY & TOXICOLOGY

HOD WELCOME

 

BRIEF HISTORY

 

VISION

PROGRAMMES

POST GRADUATE PROGRAMMES IN THE DEPARTMENT OF VETERINARY PHARMACOLOGY AND TOXICOLOGY, FACULTY OF VETERINARY MEDICINE, UNIVERSITY OF ABUJA

PROGEMMES

  • Masters of Science (Pharmacology)

  • Masters of Science (Toxicology)

  • Doctor of Philosophy (Pharmacology)

  • Doctor of Philosophy (Toxicology )

DEGREES AWARDED

  • M.Sc. (Pharmacology)

  • M.Sc. (Toxicology)

  • Ph.D. (Pharmacology)

  • Ph.D. (Toxicology)

  1. MASTER OF SCIENCE IN VETERINARY PHARMACOLOGY AND

TOXICOLOGY

Philosophy

The Master of Science Programmes in the Department of Veterinary Pharmacology and Toxicology are designed to provide the students with the required knowledge for the attainment of competence in carrying out research activities that will contribute positively in the areas of drug development, public health, livestock production, biomedical institutions and the academia.

Objectives of the programme

The objectives are to:

  1. offer advanced and broad-based courses in the field of Pharmacology and Toxicology;

  1. ensure that students use the acquired biomedical knowledge as instrument for solving health problems and improving livestock production;

  1. inculcate into the students, the skills for carrying out research according to internationally accepted standards;

  1. provide guidance for students in the application of the knowledge and skills they acquired in the field of Pharmacology and Toxicology for their career development.

Areas of Specialisation

The areas of research and specialisation include the following:

  • Neuropharmacology

  • Systemic Pharmacology (renal, cardiovascular, gastrointestinal etc)

  • Endocrine Pharmacology

  • Veterinary Pharmacy and Clinical Pharmacology

  • Ethnopharmacology/Natural Product Research

  • Chemotherapy

  • Toxicology of poisonous and venomous animals

  • Toxicology of poisonous plants

  • Environment Toxicology

Degrees to be Awarded

  • M.Sc. (Pharmacology)

  • M.Sc. (Toxicology)

Admission Requirements

In addition to the general admission requirements of the University, the candidate must possess the following qualifications to be admitted into the Masters of Science (MSc) programme of the Department of Veterinary Pharmacology and Toxicology:

  1. A Doctor of Veterinary Medicine (DVM) degree or relevant degrees such as Bachelor of Veterinary Science (BVSc) degree, MBBS, B.Pharm.

  1. A relevant Bachelor’s degree with a minimum of second class lower degree of classification

Duration of the Programme

The duration of the Master’s programme is a minimum of four (4) semesters and maximum of six (6) semesters

Mode of Study

The programme will only be run on full-time basis

Requirements for Graduation

  1. Students will be required to register for not less than 35 credit units including all the core courses and the project

  1. Students may be allowed to select not more than six (6) credit units as Elective Courses from outside the Department. Such courses must be relevant to the students’ areas of specialisation.

 

LIST OF COURSES FOR FIRST SEMESTER

COURSE CODE

COURSE TITLE

CREDIT UNITS

STATUS

VPC 811

Advanced Chemotherapy

3

Core

VPC 812

Biochemical Pharmacology

3

Core

VPC 813

Research Techniques

2

Core

VPC 814

Biostatistics

2

Core

VPC 815

Renal and Cardiovascular Pharmacology

2

Elective

VPC 816

Advanced Toxicology I

2

Core

VPC 817

Instrumentation

2

Core

VPC 818

MSc Seminar

2

Core

VPC 899

MSc Dissertation

6

Core

Total

24

LIST OF COURSES FOR SECOND SEMESTER

COURSE CODE

COURSE TITLE

CREDIT UNITS

STATUS

VPC 821

Clinical Pharmacology

3

Core

VPC 822

Advanced Immunopharmacology

2

Elective

VPC 823

Advanced Neuropharmacology

2

Core

VPC 824

Gastrointestinal Pharmacology

2

Elective

VPC 825

Endocrine Pharmacology

2

Elective

VPC 826

Advanced Toxicology II

3

Core

VPC 827

Advanced Toxicology III

3

Core

VPC 828

Ethnopharmacology

2

Elective

VPC 829

MSc Seminar

2

Core

VPC 899

MSc Dissertation

6

Core

Total

27

COURSE DESCRIPTION

VPC 811 Advanced Chemotherapy 3 credit units

Applications of antimicrobial agents for the treatment and prophylaxis of disease conditions and surgery, evaluation of antimicrobial efficacy and extra-label uses of antimicrobial agents for livestock production. Chemotherapy of protozoal infections (amoebiasis, giardiasis, trichomoniasis, trypanosomiasis, leishmaniasis), chemotherapy of helminth infections and ectoparasitism.

VPC 812 Biochemical Pharmacology 3 credit units

Routes of drug administration, drug absorption and bioavailability, phases of drug metabolism, outcome of drug metabolism, Phase I reactions, Phase II reactions, factors affecting drug metabolism, drug-drug interaction, organs involved in drug metabolism, drug toxicities, drug idiosyncracies, drug hypersensitivity, drug side-effects; role of metabolism in drug toxicity, management of drug toxicities, drug metabolism in neonates, biotransformation in young animals, biotransformation in old animals, animal breed disposition and drug metabolism and pharmacogenomics. Factors altering the kinetics of drugs at the levels of absorption, transport, distribution, metabolism and excretion. Molecular aspects of drug action at the membrane level, receptor kinetics, occupancy, rate and theories of drug action, receptor models, receptor based strategies for the development of new pharmaceuticals, gene mapping and molecular diagnosis.

VPC 813 Research Techniques 2 credit units

Principles of planning, conducting experiments and interpretation of results, management of laboratory animals, in vivo and in vitro approaches for pharmacological and toxicological research, writing of scientific papers and grant proposals and methods of scientific presentations.

VPC 814 Biostatistics 2 credit units

Principles and applications of statistical methods in biomedical research, statistical data, frequency distribution, graphical presentations of data, measurements of central tendency and dispersion, skewness probability, binomial and normal distribution, concepts of test of significance and simple tests, elements of regression and correlation, sampling techniques, simple random sampling, stratified sampling, cluster sampling and designing of experiments.

VPC 815 Renal and Cardiovascular Pharmacology 2 credit units

Fluid therapy and diuretic drugs, vasopressin and other agents influencing renal conservation of water, renin and angiotensin, therapy of myocardial ischemia, hypertension, congestive heart failure, hypercholesterolaemia, dyslipidaemia, antiarrythmic drugs, coagulants, anticoagulants and haematinics.

VPC 816 Advanced Toxicology I 2 credit units

Absorption and distribution of toxicants, metabolism of toxicants, reactive metabolites, chemical and physiological effects on xenobiotic metabolism, elimination of toxicants, chemical carcinogenesis, teratogenesis, hepatotoxicity, nephrotoxicity, neurotoxicology, endocrine system toxicology, respiratory toxicity, immunotoxicity, reproductive system toxicity, toxicity testing, forensic and clinical toxicology, prevention of toxicity.

VPC 817 Instrumentation 2 credit units

Introduction to analytical methods and procedures involving the use of modern laboratory instruments for cutting –edge research in pharmacology and toxicology.

VPC 818 MSc Seminar 2 credit units

The candidates will be required to present their research projects and/or other topics of scientific merit.

VPC 821 Clinical Pharmacology 3 credit units

Routes of drug administration, drug absorption and bioavailability, pharmacodynamics, pharmacokinetics, dose-response quantification, therapeutic index, dosing regimens, pharmaco-economics, drug-induced disease, management of body fluid and blood disorders, management of cardiac dysfunctions, management of respiratory system disorders, management of gastrointestinal tract disorders, neurological therapies, drug therapy of endocrinopathies, pain and inflammation, chemotherapy of infections and neoplasia, immunologic agents and immunodulators, gene therapy and recombinant biotechnology, essential drug policy and antimicrobial drug resistance.

VPC 822 Advanced Immunopharmacology 2 credit units

Immune response, general approach to organ transplantation therapy, biologic induction therapy, maintenance immunotherapy, therapy for established rejection, immunosuppressants (glucocorticoids, calcineurin inhibitors, antiproliferative and antimetabolic drugs, antibodies), tolerogens, immunostimulants (levamisole, Bacillus Calmette-Guérin, recombinant cytokines) and immunization (vaccines and immune globulin).

VPC 823 Advanced Neuropharmacology 2 credit units

Neurotransmission (autonomic and somatic motor nervous systems), muscarinic receptor agonists and antagonists, acetylcholinesterase inhibitors, agents acting at the neuromuscular junction and autonomic ganglia, adrenergic agonists and antagonists, 5-Hydroxytryptamine (serotonin), neurotransmission (CNS), CNS stimulants, general anaesthetics, local anaesthetics, therapeutic gases (oxygen, carbon dioxide, nitric oxide and helium), hypnotics and sedatives, drug therapy of depression and anxiety disorders, pharmacotherapy of psychosis and mania, pharmacotherapy of the epilepsies, treatment of CNS degenerative disorders, opioid analgesics, drug addiction, drug abuse and euthanatising agents.

VPC 824 Gastrointestinal Pharmacology 2 credit units

Pharmacotherapy of gastric acidity, peptic ulcers, gastroesophageal reflux disease, disorders of bowel motility and water flux, antiemetics, biliary and pancreatic diseases, inflammatory bowel disease and metabolic disorders.

VPC 825 Endocrine Pharmacology 2 credit units

Study of hormones influencing metabolism and the reproductive system, bioassays, uses of hormones as growth promoters and implication of hormone therapy.

VPC 826 Advanced Toxicology II 3 credit units

Properties of animal toxins, Arthropods, Arachnida (scorpions, spiders and ticks), Chilopoda (centipedes), Diplopoda (millipedes), Insecta, Heteroptera (true bugs), Hymenoptera (ants, bees, wasps and hornets), Lepidoptera (caterpillars, moths and butterflies), Mullosca (cone snails), lizards, snakes (snake venoms, enzymes, polypeptides, snakebite treatment, snake venom evolution), and antivenom.

Plant identification, diagnosis of plant poisoning, plant poisoning in pet animals and livestock, conditions conducive to plant poisoning, predictive and toxicity factors, prevention and treatment of plant poisoning.

VPC 827 Advanced Toxicology III 3 credit units

Environmental risk assessment (formulating the problem, analyzing exposure and effects information, characterizing risk and managing risk), environmental toxicants affecting animals and plant health (toxicants in air, water, soil, occupational and industrial toxicants), principles of ecotoxicology, avian toxicology, aquatic toxicology and toxicology of marine toxins. Analytical methods in toxicology, transport and fate of toxicants in the environment.

Risk perception, hazard identification, structure-activity relationships, in vitro and short-term tests, animal bioassays, use of epidemiological data in risk assessment, characterization of risk, quantitative risk assessment (dose-response assessment, nonthreshold approaches, models derived from mechanistic assumptions, toxicologic enhancements of the models), exposure assessment, variation in susceptibility, information resources, integration of the qualitative and quantitative aspects of risk assessment

VPC 828 Ethnopharmacology 2 credit units

Assessment of the principles of ethno-botany and ethno-pharmacology,
evaluation of the development of modern medicines from ethno-pharmacological leads, Chemistry, biosynthetic pathways, biological  and

pharmacological activities of some of the major chemical classes (alkaloids, 

terpenoids, phenolics), research methods in ethno-botany and ethno-pharmacology, ethics in exploitation and development of traditional knowledge in medicinal plants, evaluation of methods for preservation and maintenance of biological diversity of medicinal plants.

VPC 829 MSc Seminar 2 credit units

The candidates will be required to present two seminars, a pre-research seminar and a post- research seminar.

VPC 899 MSc Dissertation 6 credit units

Each candidate will be required to conduct research in an approved area in his/her field of study under the guidance of the members of the supervisory committee. The write-up of the research project will form the thesis which will be submitted for evaluation as part of the requirements for the award of the degree and it shall be defended orally.

  1. DOCTOR OF PHILOSOPHY IN VETERINARY PHARMACOLOGY AND

TOXICOLOGY

Philosophy

The Doctor of Philosophy programmes in the Department of Veterinary Pharmacology and Toxicology are designed to engage the students in research activities at the highest level of specialisation in Pharmacology and Toxicology so as to contribute significantly to the advancement of human, animal and environmental health on a global scale.

Objectives of the programme

The objectives are to:

  1. equip the students with the essential skills for implementing innovative research projects

  1. ensure that students use the acquired biomedical knowledge as instrument for solving health problems and improving livestock production

  1. ensure that the students acquire the habit and skill for adopting internationally accepted standards in carrying out research

  1. provide guidance for the students in the application of the knowledge and skills they acquired in the field of Pharmacology and Toxicology for their career development

Areas of Specialisation

The areas of research and specialisation include the following:

  • Neuropharmacology

  • Systemic Pharmacology (renal, cardiovascular, gastrointestinal etc)

  • Endocrine Pharmacology

  • Veterinary Pharmacy and Clinical Pharmacology

  • Ethnopharmacology/Natural Product Research

  • Chemotherapy

  • Toxicology of poisonous and venomous animals

  • Toxicology of poisonous plants

  • Environment Toxicology

Degrees to be Awarded

  • Ph.D (Pharmacology)

  • Ph.D (Toxicology)

Admission Requirements

In addition to the general admission requirements of the University, the candidate must possess the following:

  1. Master of Science (MSc) degree, Master of Veterinary (MVSc) degree or other relevant postgraduate degrees from University of Abuja and other reputable universities recognised by the Senate of the University of Abuja

  1. Candidates from other relevant approved Faculties/ Departments may be required to register some make up courses.

Duration for the Ph.D Programme

The duration for the programme is a minimum of six (6) semesters and a maximum of twelve (12) semesters

Mode of Study

The programme will only be run on full-time basis

Requirement for Graduation

  1. Students will be required to register for not less than 44 credit units including the thesis.

LIST OF COURSES FOR FIRST SEMESTER

COURSE CODE

COURSE TITLE

CREDIT UNITS

STATUS

VPC 911

PhD Seminar I

3

Core

VPC 999

PhD Thesis

35

Core

LIST OF COURSES FOR SECOND SEMESTER

COURSE CODE

COURSE TITLE

CREDIT UNITS

DESIGNATION

VPC 921

PhD Seminar II

3

Core

VPC 922

PhD Seminar III

3

Core

VPC 999

PhD Thesis

35

Core

COURSE DESCRIPTION

VPC 911 PhD Seminar I 3 credit units

The candidates will be required to present a pre-research seminar

VPC 921 PhD Seminar II 3 credit units

The candidates will be required to present a seminar to show work progress

VPC 922 PhD Seminar III 3 credit units

The candidates will be required to present a final seminar

VPC 999 PhD Thesis 35 credit units

GOALS/OBJECTIVES

STAFF LIST

Contact Information
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Our Faculty

Dr. Ode Okwoche Julius
Associate Professor

Dr. Ode Okwoche Julius

Qualifications: DVM, MSC, PhD. Rank: Associate Professor Research fields: Ethnopharmacology,Isolation...
Dr Gbenga Michael OLADELE
Associate Professor

Dr Gbenga Michael OLADELE

PERSONAL DATA Name: Gbenga Michael OLADELE Staff Number: ACA/1275 Department: Veterinary...
DR. ONAKPA MICHAEL MONDAY
Senior Lecturer

DR. ONAKPA MICHAEL MONDAY

I am a Nigerian Registered Veterinary Surgeon with a penchant for Research and Knowledge...
PROFESSOR SANNI SAKA
Professor of Pharmacology and Toxicology

PROFESSOR SANNI SAKA

His academic career began in 1994 at the University of Maiduguri. He has been involved...